Batubara regency, North Sumatra province, Indonesia

Approach to USD 40.000

Menzies School of Health Research Darwin

• Menzies School of Health Research (Australia).
• Mahidol Oxford Research Unit / MORU (Thailand).
• University of Melbourne (Australia).
• Arba Minch General Hospital, Ethiopia.
• Kravanh District Hospital, Pursat, Cambodia.
• Siem Pang Health center, Stung Treng, Cambodia.
• Chambak Health Center, Kampong Speu, Cambodia.
• Primary Health Care in Batubara, Sumatera, Indonesia.
• Khidmat-e-Alam Medical center, Nazimabad, Pakistan.
• Thatta Civil Hospital, Thatta, Sindh province, Pakistan.

• To assess the effectiveness of a short-course of high dose primaquine (total dose 7mg/kg given unsupervised over 7 days) compared to the current standard low dose primaquine regimen (total dose 3.5mg/kg given unsupervised over 14 days).
• To assess the effectiveness of tafenoquine (single dose of 300mg) compared to the short-course high dose primaquine regimen.
• To assess the effectiveness of tafenoquine (single dose of 300mg) compared to the standard low dose primaquine regimen.
• To assess the safety of tafenoquine compared to the high and low dose primaquine regimens.
• To assess the cost-effectiveness and feasibility of high dose primaquine and tafenoquine compared to the current low dose primaquine regimen.

On-Going